"Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth"."Interaction between acetaminophen and warfarin in adults receiving long-term oral anticoagulants: a randomized controlled trial".
A Major Drug Interaction exists between acetaminophen / ibuprofen and Symtuza. View detailed information regarding this drug interaction.

ibuprofen-diphenhydramine citrate oral decreases effects of acetaminophen-codeine oral by altering drug metabolism. Conversion of codeine to it's active form is reduced, possibly reducing the effect of codeine. Patient Drug Interactions Source: RxList.

This particular example perfectly highlights why Importance Of Monitoring Ibuprofen Acetaminophen Interactions Online is so captivating.
In 14 over-the-counter dose comparisons (acetaminophen, 10-15 mg/kg; ibuprofen, 2.5-10 mg/kg), antipyresis favored ibuprofen in 6, was similar between groups in 7, and favored acetaminophen (15 mg/kg vs ibuprofen 5 mg/kg) in 1 comparison. Both medications were well tolerated.
Kanabar D, Dale S, Rawat M. A review of ibuprofen and acetaminophen use...